THIS MEDICATION MAY CAUSE HARM TO YOUR BABY:
Available information on use during pregnancy is limited.
What is vedolizumab?
Vedolizumab is a medication that decreases inflammatory activity in the body, specifically in the human gut.
What is vedolizumab used to treat?
Vedolizumab is a prescription medication used to treat Crohn’s disease and ulcerative colitis in adults.
How does vedolizumab work?
Vedolizumab is an antibody that decreases the presence of inflammatory chemicals in the body that contribute to diseases such as Crohn’s disease and ulcerative colitis.
If I am taking vedolizumab, can it harm my baby?
Safety data in pregnant humans is lacking. Although vedolizumab has not produced adverse effects in animal studies, any adverse effects would be most likely to result while taking the medication during the second and third trimesters. One study in pregnant women exposed to vedolizumab suggested a potential increase in infection risk.
If I am taking vedolizumab and become pregnant, what should I do?
The risks to the infant should be weighed against the benefits to the mother before continuing vedolizumab therapy during pregnancy. Women on vedolizumab therapy during pregnancy are encouraged to enroll in the Vedolizumab Pregnancy Registry.
If I am taking vedolizumab, can I safely breastfeed my baby?
The effect of vedolizumab on breastfeeding infants is unknown. It is important to be cautious when administering vedolizumab while breastfeeding.
If I am taking vedolizumab, will it be more difficult to get pregnant?
Animal studies have reported no effect of vedolizumab therapy on male or female fertility.
If I am taking vedolizumab, what should I know?
It is important to speak with your doctor to determine if you should continue vedolizumab therapy during pregnancy. Information on use of vedolizumab therapy during pregnancy is limited. Vedolizumab should only be used during pregnancy if the benefit to the mother outweighs the risk to the developing baby.
If I am taking any medication, what should I know?
This report provides a summary of available information about the use of vedolizumab during pregnancy and breastfeeding. Content is from the product label unless otherwise indicated.
You may find Pregistry's expert reports about autoimmune diseases here, and reports about the individual medications used to treat immune disorders here. Additional information can also be found in the resources below.
For more information about vedolizumab during and after pregnancy, contact http://www.womenshealth.gov/ (800-994-9662 [TDD: 888-220-5446]) or check the following link:
Takeda Pharmaceuticals: Entyvio Prescribing Information