THE SAFETY OF DOXYCYCLINE HYCLATE (ACTICLATE) DURING PREGNANCY OR BREASTFEEDING
THIS MEDICATION CAN CAUSE HARM TO YOUR BABY:Limited information is available on the safety of doxycycline hyclate during pregnancy. Due to negative effects related to tooth discoloration and growth problems in infants exposed to other tetracycline antibiotics, it is generally recommended to avoid the use of doxycycline hyclate during pregnancy and breastfeeding.
What is doxycycline hyclate?
Doxycycline hyclate is a tetracycline antibiotic that is used to treat bacterial infections.
What is doxycycline hyclate used to treat?
Doxycycline hyclate is an antibiotic used to treat Rocky Mountain Spotted Fever, sexually transmitted infections, anthrax exposure, respiratory infections, and to prevent malaria, as well as for many off-label uses.
How does doxycycline hyclate work?
Doxycycline hyclate interferes with protein development in bacteria, causing the bacteria to die.
If I am taking doxycycline hyclate, can it harm my baby?
Tetracycline antibiotics do cross the human placenta to reach the developing baby. Most available information on doxycycline hyclate is during the first trimester of pregnancy. Doxycycline hyclate is not expected to cause birth defects, but further study is needed to determine the true risk of birth defects. Doxycycline hyclate can cause discoloration of infant teeth during second and third trimester use and may alter the growth of the developing baby with continued exposure.
If I am taking doxycycline hyclate and become pregnant, what should I do?
It is important that you speak with your doctor if you become pregnant while taking doxycycline hyclate. Doxycycline hyclate is used to treat Rocky Mountain Spotted Fever during pregnancy, but it is not recommended as a first line antibiotic for other conditions during pregnancy.
If I am taking doxycycline hyclate, can I safely breastfeed my baby?
Doxycycline hyclate is expected to be excreted in breast milk. The estimated amount of medication reaching the breastfeeding infant is around 6% of the maternal dose. Potential concerns with doxycycline hyclate exposure in breastfeeding infants include changes in bacteria in the stomach, diarrhea, discoloration of developing teeth, and interference with growth, particularly with prolonged exposure. The American Academy of Pediatrics considers tetracycline, an antibiotic in the same antibiotic class as doxycycline hyclate, compatible with breastfeeding. The World Health Organization recommends avoiding breastfeeding while on this medication, but does state that up to one week on this medication while breastfeeding should be safe. It is important to weigh the risks and benefits of continuing breastfeeding while taking doxycycline hyclate. Either breastfeeding or medication use are typically discontinued by women who are breastfeeding.
If I am taking doxycycline hyclate, will it be more difficult to get pregnant?
Doxycycline hyclate may affect male fertility. Doxycycline hyclate can affect the liver in pregnant women.
If I am taking doxycycline hyclate, what should I know?
It is important to speak with your doctor to determine if you should start or continue doxycycline hyclate therapy during pregnancy. Doxycycline hyclate is not considered a first line antibiotic for most conditions during pregnancy. Doxycycline hyclate should only be used for short-term (up to one week) of treatment during breastfeeding.
If I am taking any medication, what should I know?
This report provides a summary of available information about the use of tetracycline antibiotics during pregnancy and breastfeeding. Content is from the product label unless otherwise indicated.
You may find Pregistry's expert reports about infections here, and reports about the individual medications used to treat infections here. Additional information can also be found in the resources below.
For more information about doxycycline hyclate during and after pregnancy, contact http://www.womenshealth.gov/ (800-994-9662 [TDD: 888-220-5446]) or check the following link:
Aquapharm: Acticlate Prescribing Information