Oncology & Immunology
Oncology & Immunology
Expert reports about Oncology & Immunology
Methotrexate is also known as Otrexup, Rasuvo,
THE SAFETY OF METHOTREXATE DURING PREGNANCY OR BREASTFEEDING
THIS MEDICATION CAN CAUSE HARM TO YOUR BABY: Methotrexate should not be used during pregnancy or breastfeeding due to an increased risk of miscarriage, death of the baby, and birth defects including methotrexate embryopathy or fetal aminopterin-methotrexate syndrome. The highest risk of fetal aminopterin-methotrexate syndrome is 6-8 weeks after conception (or 8-10 weeks after the first day of the last menstrual period) at a dose of more than 10 mg per week. It is recommended to use this medication during pregnancy only in cancerous and noncancerous neoplastic conditions after weighing the potential risks versus benefits of use during pregnancy or while breastfeeding.
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