Infections

Expert reports about Infections


INFORMATION FOR WOMEN WHO HAVE HEMOLYTIC UREMIC SYNDROME (HUS) DURING PREGNANCY OR BREASTFEEDING

                                                                                                                                                

What is hemolytic uremic syndrome during pregnancy?

Hemolytic uremic syndrome (HUS) is a blood vessel and blood condition in which platelets (clotting cells) are destroyed, red blood cells are broken up (hemolysis) leading to anemia, with problems in small blood vessels (microangiopathy) causing kidney failure, and sometimes also damage to other organs, including the heart and brain. Outside of pregnancy, HUS typically is triggered by an intestinal infection with certain strands of Escherichia coli bacteria, and typically strikes children younger than 5 years. However, HUS also is one of several conditions with microangiopathy as the underlying mechanism that can develop in connection with pregnancy. Pregnancy-related HUS, which usually strikes during the three months following delivery (postpartum period) is called pregnancy-associated atypical HUS (p-aHUS) because it happens usually without an E. coli infection.


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